RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-17
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR;western blot;luciferase reporter assay etc.
Target
Smad7
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Downregulation of miR-17 suppresses TGF-beta1-mediated renal fibrosis through targeting Smad7
Year
2021
Function
Downregulation of miR-17 could suppress renal fibrosis mediated by TGF-BETA1 through targeting Smad7.